Isotopically Labeled Compounds
Cayman Chemical UrsodeoxycholIc AcId-d4 500ug
An internal standard for the quantification of ursodeoxycholic acid by GC- or LC-MS
Cambridge Isotope Laboratories DEOXYCHOLIC ACID (2,2,4,4,11,11-D6, 98%) 100 UG/ML IN METHANOL, 1 ML
DEOXYCHOLIC ACID (2,2,4,4,11,11-D6, 98%) 100 UG/ML IN METHANOL, 1 ML
![Revvity Health Sciences Inc UTP, [α-<sup>32</sup>P]- 800Ci/mmol 10mCi/ml EasyTide, 250 µCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812274.jpg-250.jpg)
Revvity Health Sciences Inc UTP, [α-32P]- 800Ci/mmol 10mCi/ml EasyTide, 250 µCi
UTP, [α-32P]- 800Ci/mmol 10mCi/ml EasyTide, 250 µCi
Medchemexpress LLC Fumaric acid-13C2 | 96503-56-9 | 99.9% | 118.06 g·mol-1 | C4H4O4 (13C2) | 1 MG
Fumaric acid-13C2 is a stable isotope-labeled form of fumaric acid containing two 13C atoms, provided as a white to off-white solid for use as an analytical standard and tracer in mass-spectrometry and metabolic studies. The material is characterized and documented to support reproducible analytical results.
- Stable isotope labeled with two 13C atoms.
- High purity (99.9%).
- White to off-white solid, easy to handle and weigh.
- Suitable as an internal standard for LC-MS and GC-MS assays.
- Useful for metabolic flux and tracer experiments.
- Available in small milligram pack sizes for analytical use.
- Manufacturer documentation includes SDS and COA for quality assurance.
Medchemexpress LLC (±)-Nornicotine-d4 | 66148-18-3 | 152.23 | 5 MG
(±)-Nornicotine-d4 is the deuterium labeled form of (±)-Nornicotine, a major metabolite of Nicotine. It functions as a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. This compound is known to disrupt β-catenin and ZO-1, and induces F-actin depolymerization. It also supports self-administration behavior, making it valuable for research in atherosclerosis, Alzheimer's disease, and schizophrenia. Deuteration, the process of incorporating stable heavy isotopes, has been shown to potentially affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Major metabolite of nicotine
- Partial nAChRs agonist (α7 and α6 subunits)
- Disrupts β-catenin and ZO-1
- Induces F-actin depolymerization
- Supports self-administration behavior
- Useful in research for atherosclerosis, Alzheimer's disease, and schizophrenia
Cayman Chemical 14 15Leukotriene D4
A unique LT with weak contractile activity on both guinea pig ileum and pulmonary parenchyma compared to 5-LO-derived LTs; increases vascular permeability of human endothelial cell monolayers with similar potency to that of 5-LO-derived LTs
Cambridge Isotope Laboratories Propargyl alcohol (13C3 99%) 0 25 g
Propargyl alcohol (13C3 99%) 0 25 g
Medchemexpress LLC L-tyrosine-2,3,5,6-d4 | 62595-14-6 | MFCD00079605 | 98.0% | 185.21 | C9H7D4NO3 | 10 MG
Deuterium-labeled L-tyrosine (L-tyrosine-2,3,5,6-d4) supplied as a 10 mg solid for research use. It is intended for use as an internal standard and tracer in metabolic and isotope-labeling studies and has been reported to inhibit citrate synthase activity in the posterior cortex. Not for human or clinical use.
- Deuterium-labeled internal standard for mass spectrometry and NMR.
- Chemical formula C9H7D4NO3 and molecular weight 185.21 g/mol.
- Purity (NMR) 98.0%.
- Supplied as a 10 mg solid suitable for analytical and tracer studies.
- For research use only; not for human or clinical applications.
Medchemexpress LLC Roflumilast-d4 N-Oxide | 1794760-31-8 | C17H10D4Cl2F2N2O4 | 1 MG
Roflumilast-d4 N-Oxide is a deuterium-labeled form of Roflumilast, which is a selective PDE4 inhibitor. It exhibits IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3, or PDE5 isoenzymes from various cells.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process
- Deuteration is notable for its potential to impact the pharmacokinetic and metabolic profiles of drugs
American Radiolabeled Chemicals Inc GAL D-1-14C 1 PO4 10UC
Galactose, D-1-14C 1-phosphate 10uCi in ethanol:water (7:3), 0.1 mCi/ml, S.A. 50-60 mCi/mmol, M.W. 294, Shipped in Dry Ice, Exclusive
American Radiolabeled Chemicals Inc PREG-3A-3H 250UC
Pregnan-3a-ol-20-one, 5a-9,11,12-3H(N) 250uCi in ethanol, 1 mCi/ml, S.A. 40-70 Ci/mmol, M.W. 318, Shipped in Dry Ice, Exclusive
American Radiolabeled Chemicals Inc ANG II TYR4 125I 50UC
Angiotensin II, Tyr4-125I (human) 50uCi in tris buffer, 0.05 mCi/ml, S.A. 2200 Ci/mmol, M.W. ~1171
Medchemexpress LLC 2-Phenylethanol-d5 | 35845-63-7 | 98.3% | 25 MG
2-Phenylethanol-d5 is a deuterium-labeled form of 2-Phenylethanol, a colorless liquid with a pleasant floral odor. This compound is naturally extracted from various plants like rose, carnation, hyacinth, Aleppo pine, and orange blossom. It also acts as an autoantibiotic produced by the fungus Candida albicans. Its applications include being an additive in cigarettes and a preservative in soaps due to its stability in basic conditions.
- Deuterium-labeled compound.
- Colorless liquid with a pleasant floral odor.
- Naturally occurring in several plant species.
- Exhibits autoantibiotic properties from Candida albicans.
- Used as an additive in cigarettes.
- Functions as a preservative in soaps due to high stability.
Medchemexpress LLC L-Valine-13C5,15N | 202407-30-5 | 123.10 | 5 MG
L-Valine-13C5,15N is a 13C- and 15N-labeled L-Valine, a nonlinear semiorganic material. It causes lipid peroxidation, accumulates malondialdehyde (MDA), and inhibits cyanobacteria. It also inhibits multidrug-resistant bacteria by activating the PI3K/Akt pathway and inhibiting arginase. This compound serves as a tracer and an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS, utilizing stable heavy isotopes for drug development and pharmacokinetic studies.
- 13C- and 15N-labeled L-Valine
- Inhibits cyanobacteria and multidrug-resistant bacteria
- Functions as a tracer
- Acts as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Utilizes stable heavy isotopes for drug development and pharmacokinetic studies
Medchemexpress LLC Nonanoic acid-d17 (pelargonic acid-d17) | 130348-94-6 | 100 MG
Nonanoic acid-d17 is the deuterium-labeled form of Nonanoic acid, a naturally occurring saturated fatty acid with nine carbon atoms. Deuterium incorporation into drug molecules can serve as a tracer for quantitation during drug development and has the potential to influence the pharmacokinetic and metabolic profiles of drugs. It also significantly reduces bacterial translocation, enhances antibacterial activity, and increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2.
- Deuterium labeled nonanoic acid
- Significantly reduces bacterial translocation
- Enhances antibacterial activity
- Remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS